Razumab is a recombinant humanized monoclonal antibody fragment designed for intraocular use to treat retinal disorders like wet age-related macular degeneration, retinal vein occlusion, diabetic macular edema and myopic choroidal neovascularization.
Razumab binds to a protein called vascular endothelial growth factor (VEGF). It inhibits the action of VEGF and the growth of abnormal blood vessels in the eye. These abnormal blood vessels are responsible for the loss of vision as they cause leakage into the retina.
Razumab is approved to treat wet age-related macular degeneration (AMD). It is also used to treat macular edema due to central retinal vein occlusion (CRVO) or branch retinal vein occlusion (BRVO), Myopic choroidal neovascularization and diabetic macular edema due to diabetic retinopathy.
Razumab may cause infection and inflammation in the eye, retinal detachment and cataract. Other side effects include:
If your eye develops redness, pain, sensitive to light or if you observe a change in vision, inform your doctor immediately.
Razumab is contraindicated in patients with ocular or periocular infections or in patients with known hypersensitivity to razumab or any of the excipients in Razumab.
You should immediately inform or see your doctor if you miss to receive your razumab injection.
Chances of overdose are rare as this drug is given by the doctor. However, doses as high as 2 mg razumab in 0.05 mL have been administered to patients and there were no additional unexpected adverse reactions.
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